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GAS6 Antibody (PA5-47981) in IHC (P)
Immunohistochemical analysis of GAS6 in perfusion fixed paraffin-embedded sections of mouse intestine. Samples were incubated with GAS6 polyclonal antibody (Product # PA5-47981) using a dilution of 1 µg/mL for 1 hour at room temperature followed by Anti-Goat IgG VisUCyte™ HRP Polymer Antibody. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen R... View More
产品信息
PA5-47981
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Gas6 Asp115-Pro673
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2607376
产品详细信息
In sandwich ELISAs, less than 10% cross-reactivity with recombinant human Gas6 is observed and less than 1% cross-reactivity with recombinant mouse Gas1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AXL receptor tyrosine kinase ligand; GAS 6; GAS-6; Growth arrest-specific protein 6
基因别名: Gas-6; Gas6
UniProt ID: (Mouse) Q61592
Entrez Gene ID: (Mouse) 14456
phosphatidylserine binding
receptor binding
voltage-gated calcium channel activity
calcium ion binding
protein tyrosine kinase activator activity
receptor tyrosine kinase binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
metal ion binding
receptor agonist activity
binding, bridging
extracellular matrix protein
neuron migration
positive regulation of protein phosphorylation
positive regulation of cytokine-mediated signaling pathway
positive regulation of glomerular filtration
protein phosphorylation
phagocytosis
signal transduction
enzyme linked receptor protein signaling pathway
blood coagulation
cellular response to starvation
positive regulation of gene expression
negative regulation of tumor necrosis factor-mediated signaling pathway
macrophage cytokine production
peptidyl-serine phosphorylation
fusion of virus membrane with host plasma membrane
viral genome replication
cell-substrate adhesion
positive regulation of TOR signaling
activation of protein kinase B activity
negative regulation of interferon-gamma production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of natural killer cell differentiation
positive regulation of peptidyl-serine phosphorylation
negative regulation of protein import into nucleus, translocation
regulation of ion transmembrane transport
cellular response to interferon-alpha
cellular response to drug
B cell chemotaxis
regulation of growth
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
apoptotic cell clearance
negative regulation of sequence-specific DNA binding transcription factor activity
protein kinase B signaling
positive regulation of protein kinase activity
negative regulation of transcription, DNA-templated
viral entry into host cell
receptor-mediated virion attachment to host cell
positive regulation of protein export from nucleus
positive regulation of fibroblast proliferation
negative regulation of interleukin-1 secretion
positive regulation of phagocytosis
positive regulation of protein kinase B signaling
positive regulation of protein tyrosine kinase activity
negative regulation of biomineral tissue development
positive regulation of ERK1 and ERK2 cascade
calcium ion transmembrane transport
cellular response to vitamin K
cellular response to glucose stimulus
cellular response to growth factor stimulus
protein targeting to plasma membrane
hematopoietic stem cell migration to bone marrow
negative regulation of oligodendrocyte apoptotic process
negative regulation of interleukin-6 secretion
negative regulation of fibroblast apoptotic process
positive regulation of receptor activity
negative regulation of endothelial cell apoptotic process
positive regulation of dendritic cell chemotaxis
negative regulation of dendritic cell apoptotic process
