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GAT-1 Antibody (PA5-90220) in WB
Western blot analysis of GAT-1 in extracts of various cell lines. Samples were incubated with GAT-1 Polyclonal antibody (Product # PA5-90220) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-90220
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 500-599 of human SLC6A1 (NP_003033.3).
偶联物
形式
Liquid
浓度
0.11 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805968
产品详细信息
Positive Samples: Mouse eye, Mouse brain, Rat brain; Cellular Location: Cell membrane, Membrane, Multi-pass membrane protein
Immunogen sequence: WSFFTPIIVA GVFIFSAVQM TPLTMGNYVF PKWGQGVGWL MALSSMVLIP GYMAYMFLTL KGSLKQRIQV MVQPSEDIVR PENGPEQPQA GSSTSKEAYI
靶标信息
GAT-1 (SLC6A1) The protein encoded by SLC6A1 is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GABA T-1; GABA T1; GABA transporter 1; GABA transporter protein; GABAT1; gamma-aminobutyric acid (GABA-A) transporter 1; GAT-1; Sodium- and chloride-dependent GABA transporter 1; solute carrier family 6 (neurotransmitter transporter), member 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1; Solute carrier family 6 member 1
基因别名: A730043E01; GABATHG; GABATR; Gabt; GABT1; GAT-1; GAT1; MAE; SLC6A1; XT-1; Xtrp1
UniProt ID: (Human) P30531, (Rat) P23978, (Mouse) P31648
Entrez Gene ID: (Human) 6529, (Rat) 79212, (Mouse) 232333
transport
neurotransmitter transport
chemical synaptic transmission
learning
response to toxic substance
response to sucrose
response to lead ion
positive regulation of gamma-aminobutyric acid secretion
response to purine-containing compound
gamma-aminobutyric acid transport
negative regulation of synaptic transmission, GABAergic
response to estradiol
response to cocaine
protein homooligomerization
response to calcium ion
gamma-aminobutyric acid import
transmembrane transport
mitophagy in response to mitochondrial depolarization
response to organic substance
response to organonitrogen compound
response to organic cyclic compound
amino acid transmembrane transport
sodium ion transmembrane transport
