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GATA6 Antibody (MA5-52874) in WB
Western Blot analysis of GATA6. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with GATA6 recombinant monoclonal antibody (Product # MA5-52874) with a dilution of 1:5,000, followed by HRP-conjugated goat anti-rabbit secondary antibody with a dilution of 1:20,000. Image was developed using FeQTM ECL Substrate Kit.
Product Details
MA5-52874
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB5525
Immunogen
A synthesized peptide derived from human Gata 6 (550-595AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
GATA6 is thought to be important for regulating terminal differentiation and/or proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASD9; AVSD5; DNA-binding protein GATA-GT2; GATA-binding factor 6; GATA-binding protein 6; Transcription factor GATA-6
Gene Aliases: AA410133; GATA-6; GATA6
UniProt ID: (Human) Q92908, (Rat) P46153, (Mouse) Q61169
Entrez Gene ID: (Human) 2627, (Rat) 29300, (Mouse) 14465
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor binding
RNA polymerase II repressing transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
zinc ion binding
protein kinase binding
transcription regulatory region DNA binding
enhancer sequence-specific DNA binding
DNA binding
double-stranded DNA binding
sequence-specific DNA binding
metal ion binding
DNA-binding transcription factor
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
liver development
outflow tract septum morphogenesis
type B pancreatic cell differentiation
pancreatic A cell differentiation
transcription from RNA polymerase II promoter
phospholipid metabolic process
endodermal cell fate determination
blood coagulation
male gonad development
cardiac muscle hypertrophy in response to stress
positive regulation of BMP signaling pathway
negative regulation of transforming growth factor beta1 production
negative regulation of transforming growth factor beta2 production
tube morphogenesis
response to drug
negative regulation of apoptotic process
response to estrogen
cellular protein metabolic process
cell fate commitment
positive regulation of angiogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell development
organ formation
smooth muscle cell differentiation
positive regulation of cardioblast differentiation
cardiac muscle cell differentiation
positive regulation of cardiac muscle cell proliferation
lung saccule development
Clara cell differentiation
Type II pneumocyte differentiation
intestinal epithelial cell differentiation
cardiac vascular smooth muscle cell differentiation
response to growth factor
positive regulation of cell cycle arrest
cellular response to gonadotropin stimulus
cellular response to hypoxia
cellular response to BMP stimulus
transcription, DNA-templated
response to toxic substance
regulation of gene expression
epithelial cell differentiation
pancreas development
endodermal cell differentiation
odontogenesis of dentin-containing tooth
positive regulation of apoptotic process
positive regulation of transcription, DNA-templated
cardiac muscle tissue development
response to cAMP
regulation of transcription, DNA-templated
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