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Recommended positive controls: A549, HeLa, HepG2.
Predicted reactivity: Mouse (96%), Rat (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BFA-resistant GEF 1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
基因别名: ARF1GEF; GBF1; KIAA0248
UniProt ID: (Human) Q92538
Entrez Gene ID: (Human) 8729