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Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
Gross cystic disease of the breast is benign premenopausal disorder in which cysts are a predominant pathological lesion. These cysts appear to be formed from excessive apocrine cystic secretions. This fluid is composed of several glycoproteins including a unique 15kDa monomer protein, Gross Cystic Disease Fluid Protein-15 (GCDFP15). Cytosolic analysis of normal tissue specimens from all major organs has demonstrated GCDFP15 in apocrine epithelia, lacrimal, ceruminous and Moll's glands and in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. GCDFP15 and prostate specific antigen are co-expressed in androgen receptor-positive breast tumours.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: gcdfp 15; GCDFP-15; gp17; Gross cystic disease fluid protein 15; HGNC:8993; Prolactin-induced protein; Prolactin-inducible protein; SABP; Secretory actin-binding protein
基因别名: GCDFP-15; GCDFP15; GPIP4; PIP
UniProt ID: (Human) P12273
Entrez Gene ID: (Human) 5304