Invitrogen

GCHFR Polyclonal Antibody

查看其他12个GCHFR抗体

抗体检测数据 (5)

GCHFR Antibody in Immunocytochemistry (ICC/IF)

GCHFR Antibody in Immunocytochemistry (ICC/IF)

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GCHFR Antibody (PA5-61196) in ICC/IF

Immunofluorescent staining of GCHFR in human cell line CACO-2 using a GCHFR Polyclonal Antibody (Product # PA5-61196) shows localization to nucleoplasm.

GCHFR Antibody in Immunocytochemistry (ICC/IF)

GCHFR Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GCHFR Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GCHFR Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GCHFR Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

GCHFR Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent staining of GCHFR in human cell line CACO-2 using a GCHFR Polyclonal Antibody (Product # PA5-61196) shows localization to nucleoplasm.

GCHFR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of GCHFR in human tonsil using GCHFR Polyclonal Antibody (Product # PA5-61196) shows weak to moderate cytoplasmic positivity in germinal center cells.

GCHFR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of GCHFR in human kidney using GCHFR Polyclonal Antibody (Product # PA5-61196) shows moderate cytoplasmic positivity in cells in proximal tubules.

GCHFR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of GCHFR in human testis using GCHFR Polyclonal Antibody (Product # PA5-61196) shows no positivity in cells in seminiferous ducts as expected.

GCHFR Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of GCHFR in human liver using GCHFR Polyclonal Antibody (Product # PA5-61196) shows moderate to strong cytoplasmic positivity in hepatocytes.

产品信息

PA5-61196

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

-

免疫组化（石蜡） (IHC (P))

1:50-1:200

-

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human GCHFR. Recombinant protein control fragment (Product #RP-98083).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2641913

产品详细信息

Immunogen sequence: MPYLLISTQI RMEVGPTMVG DEQSDPELMQ HLGASKRRAL GNNFYEYYVD DPPRIVLDKL ERRGFRVLSM TGVGQTLVWC LHKE

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 94%.

靶标信息

Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: GFRP; GTP cyclohydrolase 1 feedback regulatory protein; GTP cyclohydrolase I feedback regulatory protein; p35

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基因别名: GCHFR; GFRP; HsT16933; P35

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UniProt ID: (Human) P30047

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Entrez Gene ID: (Human) 2644

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enzyme inhibitor activity protein binding amino acid binding GTP-dependent protein binding GTP cyclohydrolase binding protein-binding activity modulator

nitric oxide biosynthetic process negative regulation of biosynthetic process neurotransmitter metabolic process negative regulation of GTP cyclohydrolase I activity regulation of nitric-oxide synthase activity protein heterooligomerization