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产品信息
9247-MSM1-P1
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
PCRP-GCM2-1B3
抗原
Recombinant human GCM2 protein
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control:HeLa or MCF-7 cells.
Cellular Location: Nucleus.
靶标信息
This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chorion-specific transcription factor GCMb; GCM motif protein 2; glial cells missing 2; Glial cells missing homolog 2; glial cells missing homolog b; glide/gcm protein homolog; hGCMb; RP3-417M14.3
基因别名: GCM2; GCMB; hGCMb
UniProt ID: (Human) O75603
Entrez Gene ID: (Human) 9247
