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产品信息
PA5-55414
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human GCNT2. Recombinant protein control fragment (Product #RP-90107).
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641919
产品详细信息
Immunogen sequence: EVPWKYVINT CGQDFPLKTN REIVQHLKGF KGKNITPGVL PPDHAIKRTK YVHQEHTDKG GFFVKNTNIL KTSPPHQLTI YFGTAYVALT REFVDFVLRD QRAIDLLQWS KDT
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 76%.
靶标信息
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1, 6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: beta-1,6-N-acetylglucosaminyltransferase 2; I beta-1,6-N-acetylglucosaminyltransferase; I-branching enzyme; IGNT; Ii blood group; N-acetylglucosaminyltransferase; N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase
基因别名: bA360O19.2; bA421M1.1; CCAT; CTRCT13; GCNT2; GCNT2C; GCNT5; IGNT; II; NACGT1; NAGCT1; ULG3
UniProt ID: (Human) Q8N0V5
Entrez Gene ID: (Human) 2651
glycosaminoglycan biosynthetic process
protein glycosylation
transforming growth factor beta receptor signaling pathway
multicellular organism development
positive regulation of cell proliferation
posttranscriptional regulation of gene expression
positive regulation of epithelial to mesenchymal transition
negative regulation of cell-substrate adhesion
positive regulation of cell migration
positive regulation of heterotypic cell-cell adhesion
maintenance of lens transparency
positive regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
