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GDI1 Antibody (PA5-27498) in IHC (P)
GDI1 Polyclonal Antibody detects GDI1 protein at cytosol on U87 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U87 xenograft. GDI1 Polyclonal Antibody (Product # PA5-27498) dilution: 1:200. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-27498
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 227 and 447 of Human Rab GDI alpha
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2544974
Product Specific Information
Recommended positive controls: HepG2, NIH-3T3.
Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (88%), Xenopus laevis (88%), Dog (97%), Rabbit (97%), Sheep (98%), Chimpanzee (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDI-1; Guanosine diphosphate dissociation inhibitor 1; mental retardation, X-linked 48; Oligophrenin-2; Protein XAP-4; Rab GDI alpha; Rab GDIalpha; Rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor, alpha; RABGD RABGDIA; testis secretory sperm-binding protein Li 208a
Gene Aliases: 1A; GDI1; GDIA; GDIalpha; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; XAP4
UniProt ID: (Human) P31150, (Mouse) P50396
Entrez Gene ID: (Human) 2664, (Mouse) 14567
signal transduction
protein transport
Rab protein signal transduction
positive regulation of GTPase activity
negative regulation of axonogenesis
regulation of small GTPase mediated signal transduction
response to calcium ion
oxidation-reduction process
negative regulation of protein targeting to membrane
regulation of catalytic activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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