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产品信息
H00002664-M08
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1H3
抗原
GDI1 (AAH00317, 1 a.a. approximately 447 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MDEEYDVIVL GTGLTECIPS GIMSVNGKKV LHMDRNPYYG GESSSITPLE ELYKRFQLLE GPPESMGRGR DWNVDLIPKF LMANGQLVKM LLYTEVTRYL DFKVVEGSFV YKGGKIYKVP STETEALASN LMGMFEKRRF RKFLVFVANF DENDPKTFEG VDPQTTSMRD VYRKFDLGQD VIDFTGHALA LYRTDDYLDQ PCLETVNRIK LYSESLARYG KSPYLYPLYG LGELPQGFAR LSAIYGGTYM LNKPVDDIIM ENGKVVGVKS EGEVARCKQL ICDPSYIPDR VRKAGQVIRI ICILSHPIKN TNDANSCQII IPQNQVNRKS DIYVCMISYA HNVAAQGKYI AIASTTVETT DPEKEVEPAL ELLGPIDQKF VAISDLYEPI DDGCESQVFC SCSYDATTHF ETTCNDIKDI YKRMAGTAFD FENMKRKQND VFGEAEQ
靶标信息
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GDI-1; Guanosine diphosphate dissociation inhibitor 1; mental retardation, X-linked 48; Oligophrenin-2; Protein XAP-4; Rab GDI alpha; Rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor, alpha; RABGD RABGDIA; testis secretory sperm-binding protein Li 208a
基因别名: 1A; GDI1; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; XAP4
UniProt ID: (Human) P31150
Entrez Gene ID: (Human) 2664
signal transduction
protein transport
Rab protein signal transduction
positive regulation of GTPase activity
negative regulation of axonogenesis
regulation of small GTPase mediated signal transduction
response to calcium ion
oxidation-reduction process
negative regulation of protein targeting to membrane
