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Product Details
PA5-38048
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
18 amino acid peptide near the amino terminus of human GDPD5
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2554652
Product Specific Information
A recommended positive control is mouse kidney.
At least three isoforms of GDPD5 are known to exist.
Target Information
The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth. Altered choline phospholipid metabolism is a hallmark of cancer, and the elevated expression of GDPD5 correlates with malignant choline phospholipid metabolite profiles in human breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glycerophosphocholine phosphodiesterase GDPD5; Glycerophosphodiester phosphodiesterase 2; Glycerophosphodiester phosphodiesterase domain-containing protein 5; Phosphoinositide phospholipase C GDPD5
Gene Aliases: BC024955; GDE2; GDPD5; PP1665; PP6037; PP9363; RGD1559673; UNQ1850/PRO3580
UniProt ID: (Human) Q8WTR4, (Mouse) Q640M6
Entrez Gene ID: (Human) 81544, (Mouse) 233552, (Rat) 499211
protein binding
glycerophosphodiester phosphodiesterase activity
glycerophosphocholine phosphodiesterase activity
nuclease activity
phosphoric diester hydrolase activity
hydrolase activity
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
phosphodiesterase
lipid metabolic process
spinal cord motor neuron differentiation
cerebral cortex neuron differentiation
neuron projection development
positive regulation of neuron differentiation
negative regulation of Notch signaling pathway
positive regulation of cell cycle
regulation of timing of cell differentiation
glycerol metabolic process
nervous system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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