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产品信息
PA5-28436
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 426 and 517 of Human GEF5
偶联物
形式
Liquid
浓度
0.54 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545912
产品详细信息
Recommended positive controls: A431.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARH5; DKFZp686N1969; Ephexin 3; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; p60 TIM; Rho guanine nucleotide exchange factor (GEF) 5; Rho guanine nucleotide exchange factor 5; Transforming immortalized mammary oncogene
基因别名: ARHGEF5; GEF5; P60; TIM; TIM1
UniProt ID: (Human) Q12774
Entrez Gene ID: (Human) 7984
myeloid dendritic cell chemotaxis
actin cytoskeleton organization
regulation of actin cytoskeleton organization
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of GTPase activity
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of stress fiber assembly
regulation of ERK1 and ERK2 cascade
positive regulation of podosome assembly
positive regulation of protein import
