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GGT1 Antibody (PA5-21344) in IHC (P)
GGT1 Polyclonal Antibody detects GGT1 protein at cell membrane by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. GGT1 stained by GGT1 Polyclonal Antibody (Product # PA5-21344) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-21344
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 226 of GGT1 (Uniprot ID#P19440)
偶联物
形式
Liquid
浓度
0.71 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152897
产品详细信息
Recommended positive controls: Molt-4, Neuro2A, GL261, C8D30, NIH-3T3, Raw264.7, C2C12.
Predicted reactivity: Mouse (81%), Rat (80%), Pig (85%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Glutamyltransferase (gGT) from human kidney is a membrane-bound enzyme that transfers the gamma-glutamly moiety of gamma-glutamyl compounds such as glutathione to an acceptor, which may be an amino acid or a di- or tripeptide or water. The principal functions of gGT may be hydrolysis and metabolism of glutathione. Various human gGT isoforms have been found. The molecular mass of gGT for normal kidney is 90kDa and gGT can be used as a renal cell marker.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CD224; Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1; GGT 1; glutathione hydrolase 1; Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain; Glutathione hydrolase 1 proenzyme; Leukotriene-C4 hydrolase; testicular tissue protein Li 73
基因别名: CD224; D22S672; D22S732; dwg; GGT; GGT 1; GGT-1; GGT1; Ggtp; GTG
UniProt ID: (Human) P19440, (Mouse) Q60928
Entrez Gene ID: (Human) 2678, (Mouse) 14598
regulation of immune system process
cellular amino acid metabolic process
glutamate metabolic process
leukotriene metabolic process
glutathione metabolic process
glutathione biosynthetic process
glutathione catabolic process
xenobiotic metabolic process
spermatogenesis
cysteine biosynthetic process
leukotriene biosynthetic process
zymogen activation
regulation of inflammatory response
