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GIPC1 Antibody (APZ-045-200UL) in IHC (F)
Expression of GIPC1 in mouse and rat hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse and rat brain sections with Anti-GIPC1 Antibody (#APZ-045), (1:200), followed by goat- Anti-rabbit-AlexaFluor-488. A. In mouse brain GIPC1 staining (green) appears in neurons of the pyramidal layer (P) and their apical dendrites (arrows). B. In rat brain similar staining is observed. Cell nuclei a... View More
产品信息
APZ-045-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KAPPLVENEEAEPGR, corresponding to amino acid residues 10-24 of human GIPC1, Intracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GAIP C-terminus-interacting protein; GIPC PDZ domain containing family, member 1; GLUT1 C-terminal binding protein; GLUT1 C-terminal-binding protein; GLUT1CBP; IGF-1 receptor interacting protein 1; neurophilin1-IP; PDZ domain-containing protein GIPC1; regulator of G-protein signaling 19 interacting protein 1; regulator of G-protein signalling 19 interacting protein 1; RGS-GAIP interacting protein C-terminus; RGS-GAIP interacting protein GIPC; RGS-GAIP interacting protein, C-terminus; RGS-GAIP-interacting protein; RGS19-interacting protein 1; semaF cytoplasmic domain associated protein; SemaF cytoplasmic domain-associated protein 1; SEMCAP-1; Synectin; Tax interacting protein, clone 2; Tax interaction protein 2; TIP-2
基因别名: C19orf3; GIPC; GIPC1; GLUT1CBP; Glut1CIP; Hs.6454; IIP-1; NIP; Rgs19; RGS19IP1; SEMCAP; Semcap1; SYNECTIIN; SYNECTIN; TaxIP2; TIP-2
UniProt ID: (Human) O14908, (Rat) Q9Z254, (Mouse) Q9Z0G0
Entrez Gene ID: (Human) 10755, (Rat) 83823, (Mouse) 67903
protein targeting
G-protein coupled receptor signaling pathway
chemical synaptic transmission
glutamate secretion
positive regulation of transforming growth factor beta receptor signaling pathway
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of cytokinesis
endothelial cell migration
regulation of synaptic plasticity
cell-cell adhesion
positive regulation of GTPase activity
