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GIPC1 Antibody (PA5-87978) in WB
Western blot analysis of GIPC1 in extracts of various cell lines. Samples were incubated with GIPC1 Polyclonal antibody (Product # PA5-87978) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-87978
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-333 of human GIPC1 (NP_0057071)
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804559
产品详细信息
Immunogen sequence: MPLGLGRRKK APPLVENEEA EPGRGGLGVG EPGPLGGGGS GGPQMGLPPP PPALRPRLVF HTQLAHGSPT GRIEGFTNVK ELYGKIAEAF RLPTAEVMFC TLNTHKVDMD KLLGGQIGLE DFIFAHVKGQ RKEVEVFKSE DALGLTITDN GAGYAFIKRI KEGSVIDHIH LISVGDMIEA INGQSLLGCR HYEVARLLKE LPRGRTFTLK LTEPRKAFDM ISQRSAGGRP GSGPQLGTGR GTLRLRSRGP ATVEDLPSAF EEKAIEKVDD LLESYMGIRD TELAATMVEL GKDKRNPDEL AEALDERLGD FAFPDEFVFD VWGAIGDAKV GRY; Positive Samples: A-549, HeLa, HepG2, 293T, Mouse brain, Rat brain; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein
靶标信息
GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GAIP C-terminus-interacting protein; GIPC PDZ domain containing family, member 1; GLUT1 C-terminal binding protein; GLUT1 C-terminal-binding protein; GLUT1CBP; IGF-1 receptor interacting protein 1; neurophilin1-IP; PDZ domain-containing protein GIPC1; regulator of G-protein signaling 19 interacting protein 1; regulator of G-protein signalling 19 interacting protein 1; RGS-GAIP interacting protein C-terminus; RGS-GAIP interacting protein GIPC; RGS-GAIP interacting protein, C-terminus; RGS-GAIP-interacting protein; RGS19-interacting protein 1; semaF cytoplasmic domain associated protein; SemaF cytoplasmic domain-associated protein 1; SEMCAP-1; Synectin; Tax interacting protein, clone 2; Tax interaction protein 2; TIP-2
基因别名: C19orf3; GIPC; GIPC1; GLUT1CBP; Glut1CIP; Hs.6454; IIP-1; NIP; Rgs19; RGS19IP1; SEMCAP; Semcap1; SYNECTIIN; SYNECTIN; TaxIP2; TIP-2
UniProt ID: (Human) O14908, (Rat) Q9Z254, (Mouse) Q9Z0G0
Entrez Gene ID: (Human) 10755, (Rat) 83823, (Mouse) 67903
protein targeting
G-protein coupled receptor signaling pathway
chemical synaptic transmission
glutamate secretion
positive regulation of transforming growth factor beta receptor signaling pathway
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of cytokinesis
endothelial cell migration
regulation of synaptic plasticity
cell-cell adhesion
positive regulation of GTPase activity
