Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
GLAST Antibody (PA5-34198) in IHC (P)
Immunohistochemistry analysis of GLAST in human brain, cerebellum (molecular layer and Purkinje layer). Samples were incubated with GLAST polyclonal antibody (Product # PA5-34198). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-34198
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 19 amino acid peptide from cytoplasmic domain of human SLC1A3 / GLAST.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551551
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bovine, Horse, Rabbit, Pig (100%).
Target Information
This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EAAT-1; Excitatory amino acid transporter 1; FLJ25094; GLAST; GLAST-1; Glial glutamate transporter; Glial high affinity glutamate transporter; GluT-1; glutamate and aspartate transporter; glutamate transporter; glutamate-aspartate transporter 1; glutamate-aspartate transporter 1b; glutamate/aspartate transporter; High-affinity neuronal glutamate transporter; Sodium-dependent glutamate/aspartate transporter 1; solute carrier family 1 (glial high affinity glutamate transporter), member 3; Solute carrier family 1 member 3; solute carrier family 1, member 3
Gene Aliases: AI504299; B430115D02Rik; EA6; EAAT1; GLAST; GLAST-1; GLAST1; GLU-T; GluT-1; Gmt1; I79_010950; MGluT1; SLC1A3
UniProt ID: (Bovine) P46411, (Human) P43003, (Rat) P24942, (Mouse) P56564
high-affinity glutamate transmembrane transporter activity
glutamate:sodium symporter activity
glutamate binding
metal ion binding
L-glutamate transmembrane transporter activity
amino acid transmembrane transporter activity
amino acid binding
sodium:dicarboxylate symporter activity
protein binding
symporter activity
primary active transporter
sensory perception of sound
response to light stimulus
gamma-aminobutyric acid biosynthetic process
response to wounding
response to inorganic substance
L-glutamate transport
cranial nerve development
auditory behavior
response to drug
response to amino acid
response to antibiotic
cell morphogenesis involved in neuron differentiation
positive regulation of synaptic transmission
neuromuscular process controlling balance
transepithelial transport
L-aspartate transmembrane transport
D-aspartate import
potassium ion transmembrane transport
L-glutamate import across plasma membrane
L-aspartate import across plasma membrane
chloride transmembrane transport
neurotransmitter uptake
positive regulation of defense response to virus by host
amino acid transmembrane transport
glutamate biosynthetic process
ion transport
chemical synaptic transmission
glutamate secretion
malate-aspartate shuttle
L-glutamate import
L-glutamate transmembrane transport
mitophagy in response to mitochondrial depolarization
xenophagy
glutamate metabolic process
neurotransmitter transport
sodium ion transmembrane transport
transport
dicarboxylic acid transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support