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GLP2R (extracellular) Antibody (AGR-022-200UL) in IHC
Expression of Glucagon-like peptide 2 receptor in rat hypothalamus - Immunohistochemical staining of rat hypothalamus with Anti-GLP2R (extracellular) Antibody (#AGR-022), (1:200). Glucagon-like peptide 2 receptor (green) appears in the lateral hypothalamic region axonal profiles (vertical white arrow) and nerve cell profiles (horizontal white arrows) were labeled. DAPI is used as the counterstain (blue).
产品信息
AGR-022-200UL
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KRPDDESGWMSYLSE, corresponding to amino acid residues 241-255 of rat GLP2R, 1st extracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GLP-2 receptor; GLP-2-R; GLP-2R; Glp2 receptor; Glucagon-like peptide 2 receptor; glucagon-like peptide-2 receptor
基因别名: Glp2r
UniProt ID: (Rat) Q9Z0W0
Entrez Gene ID: (Rat) 60432
