Invitrogen

GLUT1 Polyclonal Antibody

GLUT1 Antibody in Immunocytochemistry (ICC/IF)

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GLUT1 Antibody (PA1-1063) in ICC/IF

Immunofluorescent analysis of Glucose Transporter 1 using anti-Glucose Transporter 1 polyclonal antibody (Product # PA1-1063) shows staining in HMVEC Cells.

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产品信息

PA1-1063

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫细胞化学 (ICC/IF)

Assay-dependent

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产品规格

种属反应

Bovine, Mouse, Rat

已发表种属

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues S(475) D K T P E E L F H P L G A D S Q V(492) of rat GLUT1.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 1mg/mL BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2190931

产品详细信息

PA1-1063 detects GLUT1 in rat, mouse and bovine samples.

PA1-1063 has been successfully used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects a
~42 kDa protein representing GLUT1 in rat, mouse and bovine brain samples.

The PA1-1063 immunogen is a synthetic peptide corresponding to residues S(475) D K T P E E L F H P L G A D S Q V(492) of rat GLUT1. This sequence is conserved across many species including mouse, bovine, human, porcine and ovine. This peptide (Cat. # PEP-289) is available for use in neutralization and control experiments.

靶标信息

Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA-intermediates and produce ATP under hypoglycemic conditions.

Journal of neurochemistry

Hinca SB,Salcedo C,Wagner A,Goldeman C,Sadat E,Aibar MMD,Maechler P,Brodin B,Aldana BI,Helms HCC

PA1-1063 was used in Immunocytochemistry experiments to investigate glutamate dehydrogenase in respiration in brain models.

Tue Jun 01 00:00:00 UTC 2021

Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging.

Frontiers in bioengineering and biotechnology

Salman MM,Marsh G,Kusters I,Delincé M,Di Caprio G,Upadhyayula S,de Nola G,Hunt R,Ohashi KG,Gray T,Shimizu F,Sano Y,Kanda T,Obermeier B,Kirchhausen T

Published figure using GLUT1 polyclonal antibody (Product # PA1-1063) in Immunocytochemistry

Fri Aug 02 00:00:00 UTC 2024

Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging.

Frontiers in bioengineering and biotechnology

Salman MM,Marsh G,Kusters I,Delincé M,Di Caprio G,Upadhyayula S,de Nola G,Hunt R,Ohashi KG,Gray T,Shimizu F,Sano Y,Kanda T,Obermeier B,Kirchhausen T

Published figure using GLUT1 polyclonal antibody (Product # PA1-1063) in Immunocytochemistry

Fri Aug 02 00:00:00 UTC 2024

Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures.

PloS one

Tornabene E,Helms HCC,Pedersen SF,Brodin B

Published figure using GLUT1 polyclonal antibody (Product # PA1-1063) in Immunocytochemistry

Thu Apr 02 00:00:00 UTC 2020

Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes.

PloS one

Dion F,Dumayne C,Henley N,Beauchemin S,Arias EB,Leblond FA,Lesage S,Lefrançois S,Cartee GD,Pichette V

PA1-1063 was used in Western Blotting to examine the underlying mechanisms which lead to insulin resistance in chronic kidney disease, and whether this can promote type 2 diabetes development.

Tue Sep 05 00:00:00 UTC 2017

生物信息学

蛋白别名: glucose transporter glut1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; GT1; MGC141895; MGC141896; Solute carrier family 2 a 1 (facilitated glucose transporter) brain; Solute carrier family 2, facilitated glucose transporter member 1; solute carrier family 2, member 1

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基因别名: BOS_3609; Glut-1; GLUT1; GLUTB; GTG1; Gtg3; RATGTG1; SLC2A1

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UniProt ID: (Bovine) P27674, (Mouse) P17809, (Rat) P11167

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Entrez Gene ID: (Bovine) 282356, (Mouse) 20525, (Rat) 24778

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功能