Invitrogen

GLUT2 Polyclonal Antibody

FIGURE: 1 / 1

GLUT2 Antibody (720238) in WB

Western blot analysis was performed on membrane enriched cell extracts (30 µg lysate) of HepG2 (Lane 1), Caco2 (Lane 2), HEK-293 (Lane 3), NIH/3T3 (Lane 4), C2C12 (Lane 5), PC-12 (Lane 6). The blots were probed with Anti-GLUT2 Rabbit Polyclonal antibody (Product # 720238, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A ~ 57 kDa band corresponding to GLUT2 was observed in all cell lines tested. Known quantit... View More

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Product Details

720238

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptides corresponding to Human GLUT2 (aa 73-86, 264-281, 498-511)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 0.1% BSA, 30% glycerol

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2633212

Product Specific Information

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.

This antibody is predicted to react with Monkey, Pig, Horse and Cat

Target Information

Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in the gene that encode this protein cause Fanconi-Bickel syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Antidiabetic effect of sciadonic acid on type 2 diabetic mice through activating the PI3K-AKT signaling pathway and altering intestinal flora.

Frontiers in nutrition

Chen L,Jiang Q,Lu H,Jiang C,Hu W,Yu S,Xiang X,Tan CP,Feng Y,Zhang J,Li M,Shen G

720238 was used in Western Blotting to suggest that SA could reshape the structural composition of intestinal microbes, activate the PI3K/AKT/GLUT2 pathway, improve insulin resistance, and decrease blood glucose levels.

Wed Jan 11 00:00:00 UTC 2023

Early weaning induces short- and long-term effects on pancreatic islets in Wistar rats of both sexes.

The Journal of physiology

Pietrobon CB,Miranda RA,Bertasso IM,Mathias PCF,Bonfleur ML,Balbo SL,Reis MAB,Latorraca MQ,Arantes VC,de Oliveira E,Lisboa PC,de Moura EG

720238 was used in Western Blotting to investigate the mechanisms by which glycaemic homeostasis is altered in EW models through evaluations of insulin secretion and its signalling pathway in offspring.

Sat Feb 01 00:00:00 UTC 2020

The RNA-Binding Protein NONO Coordinates Hepatic Adaptation to Feeding.

Cell metabolism

Benegiamo G,Mure LS,Erikson G,Le HD,Moriggi E,Brown SA,Panda S

720238 was used in Western Blotting to study the mechanism by which feeding and fasting drive rhythmic gene expression for physiological adaptation to daily rhythm in nutrient availability.

Tue Feb 06 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: glucose transporter 2; Glucose transporter type 2, liver; GLUT-2; liver-type glucose transporter; solute carrier family 2 (facilitated glucose transporter), member 2; Solute carrier family 2, facilitated glucose transporter member 2

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Gene Aliases: AI266973; Glut-2; GLUT2; GTT2; SLC2A2

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UniProt ID: (Human) P11168, (Mouse) P14246

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Entrez Gene ID: (Human) 6514, (Mouse) 20526, (Rat) 25351

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Function(s)

insulin receptor binding glucose transmembrane transporter activity hexose transmembrane transporter activity dehydroascorbic acid transporter activity D-glucose transmembrane transporter activity transporter activity sugar:proton symporter activity transmembrane transporter activity substrate-specific transmembrane transporter activity

Process(es)

transport carbohydrate transport carbohydrate utilization glucose transport proton transport carbohydrate transmembrane transport hexose transmembrane transport glucose import transmembrane transport dehydroascorbic acid transport cation transmembrane transport carbohydrate metabolic process hexose transport response to glucose fructose transport response to peptide hormone regulation of insulin secretion glucose transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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GLUT2 Polyclonal Antibody

GLUT2 Antibody (720238) in WB

Product Details

720238

Western Blot (WB)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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