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This antibody recognizes human Glut2 expression on human Glut2-transfected NS0 cells, but not on control transfectants. This antibody detects Glut2 on the surface of the human intestinal cell line Caco2 (2) in flow cytometry and on fixed cells in immunocytochemistry tests. Based on flow cytometric tests on transfected cells, this antibody has no cross-reactivity with human Glut1 or human Glut3.
Reconstitute at 0.5 mg/mL in sterile PBS.
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in the gene that encode this protein cause Fanconi-Bickel syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glucose transporter 2; Glucose transporter type 2, liver; GLUT-2; solute carrier family 2 (facilitated glucose transporter), member 2; Solute carrier family 2, facilitated glucose transporter member 2
Gene Aliases: GLUT2; SLC2A2
UniProt ID: (Human) P11168
Entrez Gene ID: (Human) 6514
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