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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
GMNN inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Geminin; Geminin GMNN; OTTHUMP00000039393; RP3 369A17.3
基因别名: AW546347; Gem; GMNN; MGORS6
UniProt ID: (Human) O75496, (Mouse) O88513
Entrez Gene ID: (Human) 51053, (Rat) 291137, (Mouse) 57441