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产品信息
PA5-107135
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human GNAI1 (aa 146-195) (aa 146-195)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.4, with 2% sucrose
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2817851
产品详细信息
Sequence homology: Cow: 100%; Dog: 100%; Goat: 79%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 79%; Yeast: 100%; Zebrafish: 85%
靶标信息
Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain; and transducin-1 and transducin-2, proteins involved in phototransduction in retinal rods and cones, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adenylate cyclase-inhibiting G alpha protein; Gi1 protein alpha subunit; guanine nucleotide binding protein (G protein), alpha inhibiting 1; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide binding protein, alpha inhibiting 1; Guanine nucleotide-binding protein G(i) subunit alpha-1; guanine nucleotide-binding protein G(i), alpha-1 subunit
基因别名: AU046200; BPGTPB; Gi; Gialpha1; Gnai-1; GNAI1
UniProt ID: (Human) P63096, (Rat) P10824, (Mouse) B2RSH2
Entrez Gene ID: (Human) 2770, (Rat) 25686, (Mouse) 14677
magnesium ion binding
G-protein coupled receptor binding
GTPase activity
signal transducer activity
protein binding
GTP binding
GDP binding
G-protein beta/gamma-subunit complex binding
G-protein coupled serotonin receptor binding
GTPase activating protein binding
metal ion binding
nucleotide binding
guanyl nucleotide binding
heterotrimeric G-protein
protein folding
cell cycle
G-protein coupled receptor signaling pathway
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
response to peptide hormone
regulation of cAMP-mediated signaling
negative regulation of synaptic transmission
cell division
cellular response to forskolin
metabolic process
signal transduction
