Invitrogen

GNAS (R201H Mutant) Polyclonal Antibody

GNAS (R201H Mutant) Antibody in Western Blot (WB)

图: 1 / 1

GNAS (R201H Mutant) Antibody (PA5-119557) in WB

Western blot analysis of GNAS (R201H Mutant) in Non-transfected (-) and transfected (+) 293T whole cell extracts (30 µg). Sample was separated with 10% SDS-PAGE, incubated with polyclonal GNAS (R201H Mutant) antibody (Product # PA5-119557) at a dilution of 1:5000, and followed by HRP-conjugated anti-rabbit IgG.

Product Image Gallery

产品信息

PA5-119557

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:10,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GNAS (R201H Mutant).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.4 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 1% BSA, 20% glycerol

内含物

0.025% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2913130

产品详细信息

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

靶标信息

This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, which is commonly found in imprinted genes and correlates with transcript expression. This gene has an antisense transcript. One of the transcripts produced from this locus, and the antisense transcript, are both paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Additional transcript variants have been found for this gene, but the full-length nature and/or biological validity of some variants have not been determined. [provided by RefSeq, Jun 2015]

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: Adenylate cyclase-stimulating G alpha protein; Alternative gene product encoded by XL-exon; Extra large alphas protein; G protein subunit alpha S; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1; guanine nucleotide regulatory protein; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; NESP55; neuroendocrine secretory protein; Neuroendocrine secretory protein 55; Protein ALEX; secretogranin VI; XLalphas

查看更多收起

基因别名: AHO; C20orf45; GNAS; GNAS1; GPSA; GSA; GSP; NESP; POH; SCG6; SgVI

查看更多收起

UniProt ID: (Human) Q5JWF2

查看更多收起

Entrez Gene ID: (Human) 2778

查看更多收起

功能