Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA1-724
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Sheep
已发表种属
Mouse,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic Peptide: K(18) L K E D A E K D A R T V K(31) C
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2247711
产品详细信息
PA1-724 detects rod transducin alpha (Tr alpha) from bovine outer rod segments and sheep retinal extract.
PA1-724 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~38 kDa protein representing Tr alpha from sheep retinal extract.
The PA1-724 immunizing peptide corresponds to amino acid residues 18-31 from human Tr alpha. This peptide (Cat. # PEP-153) is available for use in neutralization and control experiments.
靶标信息
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; Guanine nucleotide-binding protein G(t) subunit alpha-1; guanine nucleotide-binding protein G(T), alpha-1 subunit; rod-type transducin alpha subunit; Tr alpha; Transducin alpha-1 chain; transducin, rod-specific
基因别名: BOS_20922; CSNB1G; CSNBAD3; GBT1; GNAT1; GNATR
UniProt ID: (Human) P11488, (Bovine) P04695
Entrez Gene ID: (Human) 2779, (Sheep) 101121976, (Bovine) 281794
detection of chemical stimulus involved in sensory perception of bitter taste
protein folding
signal transduction
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
visual perception
phototransduction, visible light
cell proliferation
response to light stimulus
response to light intensity
rhodopsin mediated signaling pathway
regulation of rhodopsin mediated signaling pathway
eye photoreceptor cell development
detection of light stimulus involved in visual perception
sensory perception of umami taste
positive regulation of cyclic-nucleotide phosphodiesterase activity
negative regulation of cyclic-nucleotide phosphodiesterase activity
retina development in camera-type eye
cellular response to electrical stimulus
phototransduction
