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Immunogen sequence: MSATNNIAQA RKLVEQLRIE AGIERIKVSK AASDLMSYCE QHARNDPLLV GVPASENPFK DKKPCIIL; Positive Samples: Mouse brain, Rat brain; Cellular Location: Cell membrane, Cytoplasmic side, Lipid-anchor
GNG7 is a Guanine nucleotide-binding protein (G proteins) and are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilization of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: guanine nucleotide binding protein (G protein), gamma 7 subunit; guanine nucleotide binding protein, gamma 7; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Gene Aliases: AI840417; Gng7; Gngt7
UniProt ID: (Rat) P43425, (Mouse) Q61016
Entrez Gene ID: (Rat) 58979, (Mouse) 14708
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