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产品信息
PA5-75621
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human GNG8.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719349
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the βγ subunits. It is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the γ as well as the α and β subunits and that preferential associations between members of subunit families increase G protein functional diversity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G-protein gamma 8 subunit; Gamma-9; Ggamma 9; Ggamma9; guanine nucleotide binding protein (G protein), gamma 8; guanine nucleotide binding protein (G protein), gamma 8 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
基因别名: G(y)8; GNG8; GNG9; GNGT9
UniProt ID: (Human) Q9UK08, (Rat) P63077, (Mouse) P63078
Entrez Gene ID: (Human) 94235, (Rat) 245986, (Mouse) 14709
