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产品信息
PA5-120578
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-91 of human GNPNAT1 (NP_932332.1).
偶联物
形式
Liquid
浓度
2.72 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914150
产品详细信息
Positive test controls include: HT-29, LO2, BxPC-3, mouse kidney, mouse lung, rat liver, rat kidney.
Immunogen sequence: MKPDETPMFD PSLLKEVDWS QNTATFSPAI SPTHPGEGLV LRPLCTADLN RGFFKVLGQL TETGVVSPEQ FMKSFEHMKK SGDYYVTVVE D
靶标信息
Glucosamine-6 phosphate-N-acetyl Transferase (GNPNAT1) is a key enzyme in the hexosamine biosynthetic pathway. It converts D-glucosamine 6-phosphate to N-acetyl-D-glucosamine 6-phosphate, the acetylation step allowing carbon and nitrogen enter into the hexosamine biosynthetic pathway. Recently inhibition of GNPNAT1 has been reported to promote proliferation and aggressiveness of castration-resistant prostate cancer. (27194471).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Glucosamine 6-phosphate N-acetyltransferase; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase 1; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase; Protein EMeg32
基因别名: AU017428; AU040593; EMeg32; GNA1; GNPNAT; GNPNAT1; Gpnat1; Gsnpat; RGD1563144
UniProt ID: (Human) Q96EK6, (Mouse) Q9JK38
Entrez Gene ID: (Human) 64841, (Mouse) 54342, (Rat) 498486
