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产品信息
PA5-31051
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 166 of Human GPD1
偶联物
形式
Liquid
浓度
0.51 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548525
产品详细信息
Recommended positive controls: A549.
Predicted reactivity: Mouse (91%), Rat (91%), Pig (91%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: glycerol 3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 1 (soluble); Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; glycerophosphate dehydrogenase; GPD-C; GPDH-C
基因别名: GPD-C; GPD1; Gpd3; GPDH; GPDH-C; HTGTI
UniProt ID: (Human) P21695, (Rat) O35077
Entrez Gene ID: (Human) 2819, (Rat) 60666
gluconeogenesis
glycerophosphate shuttle
phosphatidic acid biosynthetic process
triglyceride biosynthetic process
positive regulation of glycolytic process
glycerol-3-phosphate catabolic process
cellular response to cAMP
cellular response to tumor necrosis factor
carbohydrate metabolic process
glycerol-3-phosphate metabolic process
NADH oxidation
NADH metabolic process
glycerolipid metabolic process
oxidation-reduction process
