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GPD2 Antibody (PA5-120446) in WB
Western blot analysis of GPD2 in various lysates. Samples were incubated with GPD2 Polyclonal antibody (Product # PA5-120446) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-120446
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 25-325 of human GPD2 (NP_000399.3).
偶联物
形式
Liquid
浓度
1.02 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914018
产品详细信息
Positive test controls include: THP-1, Mouse skeletal muscle. The target is usually found in the following locations: Mitochondrion.
Immunogen sequence: SQFAHYRRKQ MNLAYVKAAD CISEPVNREP PSREAQLLTL QNTSEFDILV IGGGATGSGC ALDAVTRGLK TALVERDDFS SGTSSRSTKL IHGGVRYLQK AIMKLDIEQY RMVKEALHER ANLLEIAPHL SAPLPIMLPV YKWWQLPYYW VGIKLYDLVA GSNCLKSSYV LSKSRALEHF PMLQKDKLVG AIVYYDGQHN DARMNLAIAL TAARYGAATA NYMEVVSLLK KTDPQTGKVR VSGARCKDVL TGQEFDVRAK CVINATGPFT DSVRKMDDKD AAAICQPSAG VHIVMPGYYS P
靶标信息
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FAD-linked glycerol-3-phosphate dehydrogenase; glycerol phosphate dehydrogenase 1, mitochondrial; Glycerol-3-phosophate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase 2, mitochondrial; Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mGDH; mitochondrial glycerol-3-phosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase; mitohondrial glycerophosphate dehydrogenase gene; mtGPD; mtGPDH gene, promoter region and alternative transcripts; Protein TISP38; testicular tissue protein Li 76
基因别名: AA408484; AI448216; AU021455; AW494132; GDH2; Gdm1; Gpd-m; GPD2; GPDH; Gpdh-m; GPDM; mGPDH; mtGPDH; TISP38
UniProt ID: (Human) P43304, (Mouse) Q64521, (Rat) P35571
Entrez Gene ID: (Human) 2820, (Mouse) 14571, (Rat) 25062
