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Sequence of this protein is as follows: MAFQKAVKGT LVGGGALATV LGLSQFAHYR RKQMNLAYVK AADCISEPVN REPPSREAQL LTLQNTSEFD ILVIGGGATG SGCALDAVTR GLKTALVERD DFSSGTSSRS TKLIHGGVRY LQKAIMKLDI EQYRMVKEAL HERANLLEIA PHLSAPLPIM LPVYKWWQLP YYWVGIKLYD LVAGSNCLKS SYVLSKSRAL EHFPMLQKDK LVGAIVYYDG QHNDARMNLA IALTAARYGA ATANYMEVVS LLKKTDPQTG KVHVSGARCK DVLTGQEFDV RAKCVINATG PFTDSVRKMD DKDAAAICQP SAGVHIVMPG YYSPESMGLL DPATSDGRVI FFLPWQKMTI AGTTDTPTDV THHPIPSEED INFILNEV
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: glycerol-3-phosphate dehydrogenase 2 (mitochondrial); Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mGDH; mitochondrial glycerol-3-phosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase; mitohondrial glycerophosphate dehydrogenase gene; mtGPD; testicular tissue protein Li 76
基因别名: GDH2; GPD2; GPDM; mGPDH
UniProt ID: (Human) P43304
Entrez Gene ID: (Human) 2820