Alomone Labs, LTD

GPER (GPR30) Polyclonal Antibody

查看其他13个GPR30抗体
说明书
实验方案
技术支持
说明书
实验方案
技术支持

产品信息

AER-050-200UL

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:200
-

免疫组化 (IHC)

Assay-dependent
-
产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)ETFRDKLRLYVAQK, corresponding to amino acid residues 329-342 of rat GPER, Intracellular, C-terminus
查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.85 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).

靶标信息

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
引用该产品

生物信息学

蛋白别名: Chemoattractant receptor-like 2; chemokine receptor-like 2; constitutively expressed peptide-like receptor like; G protein-coupled estrogen receptor 1; G protein-coupled receptor 30; G-protein coupled estrogen receptor 1; G-protein coupled receptor 30; G-protein coupled receptor 41; Membrane estrogen receptor; mER

查看更多 收起

基因别名: 6330420K13Rik; Ceprl; CMKRL2; FEG-1; GPCR-Br; Gper; Gper1; Gpr30; GPR41

查看更多 收起

UniProt ID: (Rat) O08878, (Mouse) Q8BMP4

查看更多 收起

Entrez Gene ID: (Rat) 171104, (Mouse) 76854

查看更多 收起

功能
chromatin binding steroid hormone receptor activity G-protein coupled receptor activity steroid binding drug binding mineralocorticoid receptor activity estrogen receptor activity hormone binding signal transducer activity G-protein coupled receptor
参与通路
positive regulation of protein phosphorylation positive regulation of neurotransmitter secretion negative regulation of leukocyte activation inflammatory response positive regulation of cytosolic calcium ion concentration positive regulation of cell proliferation negative regulation of cell proliferation positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway positive regulation of gene expression negative regulation of gene expression positive regulation of phosphatidylinositol 3-kinase signaling neuronal action potential apoptotic chromosome condensation nuclear fragmentation involved in apoptotic nuclear change positive regulation of cell migration intracellular steroid hormone receptor signaling pathway positive regulation of cAMP biosynthetic process mineralocorticoid receptor signaling pathway positive regulation of insulin secretion positive regulation of inositol trisphosphate biosynthetic process positive regulation of apoptotic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process steroid hormone mediated signaling pathway positive regulation of MAPK cascade innate immune response negative regulation of fat cell differentiation positive regulation of epidermal growth factor receptor signaling pathway positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of vasodilation positive regulation of transcription from RNA polymerase II promoter negative regulation of inflammatory response positive regulation of neurogenesis negative regulation of DNA metabolic process negative regulation of lipid biosynthetic process positive regulation of release of sequestered calcium ion into cytosol regulation of cytosolic calcium ion concentration positive regulation of ERK1 and ERK2 cascade positive regulation of uterine smooth muscle contraction negative regulation of cell cycle arrest cellular response to glucose stimulus cellular response to tumor necrosis factor cellular response to peptide hormone stimulus cellular response to mineralocorticoid stimulus cellular response to estradiol stimulus positive regulation of establishment of protein localization to plasma membrane positive regulation of release of cytochrome c from mitochondria positive regulation of endothelial cell apoptotic process positive regulation of extrinsic apoptotic signaling pathway immune system process transcription from RNA polymerase II promoter apoptotic process cell cycle signal transduction G-protein coupled receptor signaling pathway nervous system development cell differentiation
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持