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PA1-20430 detects G Protein-Coupled Receptor HM74 in human samples.
Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: G protein-coupled receptor 109B; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; GTP-binding protein; hydroxy-carboxylic acid receptor 3; Hydroxycarboxylic acid receptor 3; Niacin receptor 2; Nicotinic acid receptor 2; putative chemokine receptor
基因别名: GPR109B; HCA3; HCAR3; HM74; HM74B; NIACR2; Puma-g; PUMAG
UniProt ID: (Human) P49019
Entrez Gene ID: (Human) 8843