Invitrogen

GPR41 Polyclonal Antibody

GPR41 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 4

GPR41 Antibody (PA5-33533) in IHC (P)

Immunohistochemistry analysis of GPR41 in human Lung, Adenocarcinoma. Samples were incubated with GPR41 polyclonal antibody (Product # PA5-33533). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Image Gallery

产品信息

PA5-33533

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

5 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic 16 amino acid peptide from internal region of human FFAR3.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.1% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2550913

产品详细信息

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Goat (81%).

Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.

靶标信息

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPRs translate extracellular signals into intracellular signals (a process called G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR41 (G-protein coupled receptor 41), also known as FFAR3 (Free fatty acid receptor 3), is a 346 amino acid multi-pass membrane protein that belongs to the G protein-coupled receptor family. Expressed at high levels in adipose tissue and at lower levels throughout the body, GPR41 functions as a receptor for short chain fatty acids via elevation of intracellular calcium levels and inhibition of adenylyl cyclase.

仅用于科研。不用于诊断过程。未经明确授权不得转售。