Invitrogen

GPS2 Polyclonal Antibody

GPS2 Antibody in Immunocytochemistry (ICC/IF)

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GPS2 Antibody (PA5-30953) in ICC/IF

GPS2 Polyclonal Antibody detects GPS2 protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: GPS2 protein stained by GPS2 Polyclonal Antibody (Product # PA5-30953) diluted at 1:500. Red: Phalloidin, a cytoskeleton marker, diluted at 1:200.

GPS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-30953

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein fragment corresponding to a region within amino acids 1 and 253 of Human GPS2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2548427

产品详细信息

Recommended positive controls: A431, HeLa.

Predicted reactivity: Mouse (98%), Rat (98%), Bovine (98%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

仅用于科研。不用于诊断过程。未经明确授权不得转售。