Invitrogen

GRHL2 Polyclonal Antibody

GRHL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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GRHL2 Antibody (PA5-41639) in IHC (P)

Immunohistochemistry (paraffin-embedded) analysis of human brain using an anti-GRHL2 polyclonal antibody (Product # PA5-41639). Primary antibody dilution: 5 µg/mL.

GRHL2 Antibody in Immunohistochemistry (IHC)

GRHL2 Antibody in Western Blot, Immunohistochemistry (WB, IHC)

Product Image Gallery

GRHL2 Antibody — GRHL2 promotes NSCLC cell growth and colony formation. H1299 cells were transfected with indicated siRNAs or not transfected. A. Western blot of GRHL2 to check the knockdown efficiency of siRNAs in the indicated cell lines; ß-actin was used as a loading control. B. Growth in low serum. H1299 cells werecultured in 1640 supplemented with 1% serum (low serum) or 10% serum (normal serum). After the indicated time, cells were trypsinized and counted. Data represent the average of three independent experiments. C. Colony formation assay. After the indicated times, H1299 were fixed and stained with crystal violet. Representative Wells were photographed and shown. {KD}

产品信息

PA5-41639

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

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免疫组化 (IHC)

Assay-Dependent

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免疫组化（石蜡） (IHC (P))

5 µg/mL

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human GRHL2

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2607284

产品详细信息

Peptide sequence: VEKIAKLYKK SKKGILVNMD DNIIEHYSNE DTFILNMESM VEGFKVTLME

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

靶标信息

The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.

American journal of translational research

Pan X,Zhang R,Xie C,Gan M,Yao S,Yao Y,Jin J,Han T,Huang Y,Gong Y,Wang J,Yu B

Published figure using GRHL2 polyclonal antibody (Product # PA5-41639) in Western Blot

Wed Sep 30 00:00:00 UTC 2020

GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.

American journal of translational research

Pan X,Zhang R,Xie C,Gan M,Yao S,Yao Y,Jin J,Han T,Huang Y,Gong Y,Wang J,Yu B

Published figure using GRHL2 polyclonal antibody (Product # PA5-41639) in Western Blot

Wed Sep 30 00:00:00 UTC 2020

生物信息学

蛋白别名: Brother of mammalian grainyhead; grainyhead-like 2; Grainyhead-like protein 2 homolog; grainyhead-like transcription factor 2; Transcription factor CP2-like 3

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基因别名: BOM; DFNA28; ECTDS; GRHL2; TFCP2L3

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UniProt ID: (Human) Q6ISB3

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Entrez Gene ID: (Human) 79977

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功能

intronic transcription regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding chromatin DNA binding sequence-specific DNA binding DNA-binding transcription factor

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