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Positive Samples: HeLa, mouse kidney
Immunogen sequence: SLLPQSLAAA AAVPTRSYSQ ESKTTYLEDL PPPPEYELAP SKLEEEVDDV FLIRAQGLPW SCTMEDVLNF FSDCRIRNGE NGIHFLLNRD GKRRGDALIE M
G-rich sequence factor 1 (GRSF1) is a regulator of post-transcriptional mitochondrial gene expression. It required for assembly of the mitochondrial ribosome and for recruitment of mRNS and IncRNA. GRSF1 binds RNAs containing the 14 base G-rich element. It preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-NDS - each of which contains multiple consensus binding sequences.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: G-rich sequence factor 1; GRSF-1
基因别名: BB232551; C80280; D5Wsu31e; GRSF1
UniProt ID: (Human) Q12849, (Mouse) Q8C5Q4
Entrez Gene ID: (Human) 2926, (Mouse) 231413, (Rat) 305256