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GSK3B Antibody (PA5-95845) in IP
Immunoprecipitation of GSK3B in 200 μg extracts of LO2 cells. Samples were precipitated with 3 μg GSK3B Polyclonal antibody (Product # PA5-95845). Western blot was performed from the immunoprecipitate using GSK3B Polyclonal antibody (Product # PA5-95845) at a dilution of 1:1,000.
产品信息
PA5-95845
产品规格
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 350-420 of GSK3β (NP_0011396281)
偶联物
形式
Liquid
浓度
0.77 mg/mL
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2807647
产品详细信息
Immunogen sequence: LPNGRDTPAL FNFTTQELSS NPPLATILIP PHARIQAAAS TPTNATAASD ANTGDRGQTN NAASASASNS T
靶标信息
GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
