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Product Details
PA5-21675
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 30 and 241 of GSTO1 (Uniprot ID#P78417)
Conjugate
Form
Liquid
Concentration
0.75 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11156430
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, mouse colon.
Predicted reactivity: Rhesus Monkey (97%), Chimpanzee (99%), Bovine (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 21; glutathione S-transferase like; Glutathione S-transferase omega 1-1; Glutathione S-transferase omega-1; Glutathione transferase omega 1 (GSTO 1-1) (p28); Glutathione-dependent dehydroascorbate reductase; glutathione-S-transferase like; GSTO 1-1; GSTO-1; MMA(V) reductase; Monomethylarsonic acid reductase; p28; RP11-99N20.1; S-(Phenacyl)glutathione reductase; SPG-R
Gene Aliases: AA407097; AI194287; AU018802; GSTO 1-1; GSTO1; GSTTLP28; GSTX; Gtsttl; HEL-S-21; P28; SPG-R
UniProt ID: (Human) P78417, (Mouse) O09131
Entrez Gene ID: (Human) 9446, (Mouse) 14873
metabolic process
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
L-ascorbic acid metabolic process
L-ascorbic acid biosynthetic process
xenobiotic catabolic process
oxidation-reduction process
negative regulation of ryanodine-sensitive calcium-release channel activity
positive regulation of ryanodine-sensitive calcium-release channel activity
cellular response to arsenic-containing substance
glutathione metabolic process
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
methylation
cellular oxidant detoxification
glutathione derivative biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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