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Immunogen sequence: MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP TLKIDGITIH QSLAIIEYLE EMRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRA; Positive Samples: Mouse liver; Cellular Location: Cytoplasm
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: glutathione S-transferase alpha 3; Glutathione S-transferase zeta 1; glutathione transferase zeta 1; GSTZ1-1; MAAI; Maleylacetoacetate isomerase
基因别名: Gstz1; MAAI
UniProt ID: (Rat) P57113, (Mouse) Q9WVL0
Entrez Gene ID: (Rat) 681913, (Mouse) 14874