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GTF2H4 Antibody (PA5-103346) in IHC (P)
Immunohistochemistry analysis of GTF2H4 in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with GTF2H4 polyclonal antibody (Product # PA5-103346) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-103346
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human GTF2H4(Accession Q92759), corresponding to amino acid residues L108-V158.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852691
产品详细信息
Antibody detects endogenous levels of total GTF2H4.
靶标信息
GTF2H4 belongs to the TFB2 family. It is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Basic transcription factor 2 52 kDa subunit; BTF2 p52; General transcription factor IIH polypeptide 4; General transcription factor IIH subunit 4; general transcription factor IIH, polypeptide 4, 52kDa; TFIIH basal transcription factor complex p52 subunit; TFIIH transcription/DNA repair factor p52 subunit
基因别名: AW545633; BTF2 p52; GTF2H4; P52; TFB2; TFIIH
UniProt ID: (Human) Q92759, (Mouse) O70422
Entrez Gene ID: (Human) 2968, (Rat) 294236, (Mouse) 14885
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
ATP-dependent DNA helicase activity
protein kinase activity
protein binding
DNA-dependent ATPase activity
RNA polymerase II carboxy-terminal domain kinase activity
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
nucleotide-excision repair, DNA duplex unwinding
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
nucleotide-excision repair, DNA incision
phosphorylation of RNA polymerase II C-terminal domain
global genome nucleotide-excision repair
protein phosphorylation
DNA duplex unwinding
