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GTF2I Antibody (MA5-42491) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human stomach carcinoma tissue using GTF2I Recombinant Monoclonal Antibody (Product # MA5-42491). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the GTF2I ant... View More
产品信息
MA5-42491
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JE56-20
抗原
Synthetic peptide within N-terminal Human TFII I
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2911632
产品详细信息
Positive Control: A431 cell lysate, Jurkat cell lysate, Hela cell lysate, MCF-7 cell lysate, PC-12 cell lysate, rat kidney tissue, human tonsil tissue, human thyroid tissue, human colon carcinoma tissue, human skin tissue, human spleen tissue, human breast carcinoma tissue, human stomach carcinoma tissue, human small intestine tissue, human pancreas tissue.
Subcellular Location: Nucleus, Cytoplasm.
靶标信息
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11. 23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BAP-135; Bruton tyrosine kinase-associated protein 135; BTK-associated protein, 135kD; General transcription factor II-I; GTFII-I; OTTHUMP00000209509; SPIN; SRF-Phox1-interacting protein; TFII-I; tfiii; Williams-Beuren syndrome chromosomal region 6 protein; Williams-Beuren syndrome chromosome region 6
基因别名: BAP135; BTKAP1; DIWS; GTF2I; Gtf2ird1; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6
UniProt ID: (Human) P78347, (Rat) Q5U2Y1
Entrez Gene ID: (Human) 2969, (Rat) 353256
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
signal transduction
transition between slow and fast fiber
negative regulation of angiogenesis
negative regulation of cytosolic calcium ion concentration
transcription, DNA-templated
regulation of transcription, DNA-templated
