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产品信息
PA5-67046
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2665116
产品详细信息
Immunogen sequence: FWRFKLFLLRI LYQSMQKTPS EALWKPTHED SKILLVDSPG MGNADDEQQE EGTSSKQVVK QGLQERSKEG DVEEPTDDSL PT
Highest antigen sequence identity to the following orthologs - mouse 82%, rat 81%.
靶标信息
Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: general transcription factor 3C 4; General transcription factor 3C polypeptide 4; general transcription factor IIIC, polypeptide 4, 90kDa; TF3C-delta; TFIIIC 90 kDa subunit; Transcription factor IIIC 90 kDa subunit; Transcription factor IIIC subunit delta
基因别名: GTF3C4; KAT12; TF3C-delta; TFIII90; TFIIIC290; TFIIIC90; TFIIICDELTA
UniProt ID: (Human) Q9UKN8
Entrez Gene ID: (Human) 9329
transcription, DNA-templated
transcription from RNA polymerase III promoter
transcription initiation from RNA polymerase III promoter
histone acetylation
5S class rRNA transcription from RNA polymerase III type 1 promoter
tRNA transcription from RNA polymerase III promoter
positive regulation of catalytic activity
