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Antibody detects endogenous levels of total GTSE1.
The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: G-2 and S-phase expressed 1; G2 and S phase-expressed protein 1; GTSE-1; Protein B99; Protein B99 homolog
基因别名: B99; Gtse-1; GTSE1
UniProt ID: (Human) Q9NYZ3, (Mouse) Q8R080
Entrez Gene ID: (Human) 51512, (Mouse) 29870