Invitrogen

GTSE1 Polyclonal Antibody

GTSE1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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GTSE1 Antibody (PA5-26879) in IHC (P)

Immunohistochemistry analysis of GTSE1 in formalin fixed and paraffin embedded brain tissue. Samples were incubated with GTSE1 polyclonal antibody (Product # PA5-26879) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.

GTSE1 Antibody in Western Blot, Immunohistochemistry (WB, IHC)

GTSE1 Antibody in Immunohistochemistry (IHC)

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产品信息

PA5-26879

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:10-1:50

流式细胞分析 (Flow)

1:10-1:50

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 690-717 amino acids from the C-terminal region of human GTSE1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2544379

产品详细信息

This antibody is predicted to react with mouse based on sequence homology.

靶标信息

The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Downregulation of GTSE1 leads to the inhibition of proliferation, migration, and Warburg effect in cervical cancer by blocking LHDA expression.

The journal of obstetrics and gynaecology research

Chen L,Zhong Y,Yang X,Zhang Q,Wu X

PA5-26879 was used in Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot to demonstrate that downregulation of GTSE1 led to significant inhibitions in cell proliferation, migration, tumorigenesis, and Warburg effect in cervical cancer by blocking the expression of LHDA.