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Galectin 3 Antibody (PA5-34819) in ICC/IF
Galectin3 antibody detects Galectin3 protein at cytoplasm by immunofluorescent analysis. Sample: MCF-7 cells were fixed in ice-cold MeOH for 5 min. Green: Galectin3 protein stained by Galectin3 antibody (Product # PA5-34819) diluted at 1:1,000. Blue: Hoechst 33342 staining. Scale bar = 10 μm.
产品信息
PA5-34819
应用
建议稀释比
已发表文章
产品规格
种属反应
Dog,
Human,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 184 of Galectin3 (Uniprot ID#P17931)
偶联物
形式
Liquid
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2552171
产品详细信息
Recommended positive controls: HeLa, A549, H1299, HCT116, MCF-7, Recombinant LGALS3 protein, rat colon.
Predicted reactivity: Rhesus Monkey (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 35 kDa lectin; advanced glycation end-product receptor 3; beta-galactosides-binding lectin; Carbohydrate-binding protein 35; CBP 35; CBP-30; epsilon BP; Gal-3; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; Galectin-3; Galectin3; IgE binding protein; IgE-binding protein; L-29; L-31; Laminin-binding protein; lectin galactoside-binding soluble 3 protein; Lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); MAC-2 antigen
基因别名: AGE-R3; CBP 35; CBP30; CBP35; Gal-3; GAL3; GALBP; Galectin-3; GALIG; L-34; L31; LGALS2; LGALS3; MAC2
UniProt ID: (Human) Q96J47, (Rat) P08699
Entrez Gene ID: (Human) 3958, (Dog) 404021, (Rat) 83781
monocyte chemotaxis
mRNA processing
RNA splicing
neutrophil chemotaxis
epithelial cell differentiation
regulation of T cell proliferation
innate immune response
negative regulation of endocytosis
eosinophil chemotaxis
macrophage chemotaxis
negative regulation of T cell receptor signaling pathway
positive chemotaxis
regulation of T cell apoptotic process
mononuclear cell migration
positive regulation of mononuclear cell migration
positive regulation of calcium ion import
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of immunological synapse formation
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
positive regulation of dendritic cell differentiation
negative regulation of extrinsic apoptotic signaling pathway
positive regulation of protein complex assembly
positive regulation of protein localization to plasma membrane
skeletal system development
signal transduction
positive regulation of cell proliferation
positive regulation of serotonin secretion
extracellular matrix organization
negative regulation of apoptotic process
positive regulation of angiogenesis
negative regulation of cell proliferation in bone marrow
