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产品信息
PA5-79596
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived mouse Galectin 3 recombinant protein (Position: K153-I264).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2746711
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; CBP-30; epsilon BP; Gal-3; Galactose-specific lectin 3; Galectin-3; Galectin3; IgE binding protein; IgE-binding protein; L-29; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3 protein; Lectin L-29; lectin, galactose binding, soluble 3; Mac-2 antigen
基因别名: AGE-R3; CBP30; gal-3; gal3; GBP; L-34; Lgals3; Mac-2
UniProt ID: (Rat) P08699
Entrez Gene ID: (Mouse) 16854, (Rat) 83781
skeletal system development
immune system process
monocyte chemotaxis
mRNA processing
signal transduction
positive regulation of cell proliferation
RNA splicing
positive regulation of serotonin secretion
cell differentiation
extracellular matrix organization
neutrophil chemotaxis
regulation of T cell proliferation
negative regulation of apoptotic process
innate immune response
positive regulation of angiogenesis
negative regulation of endocytosis
eosinophil chemotaxis
macrophage chemotaxis
negative regulation of T cell receptor signaling pathway
positive chemotaxis
regulation of T cell apoptotic process
mononuclear cell migration
positive regulation of mononuclear cell migration
positive regulation of calcium ion import
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of cell proliferation in bone marrow
negative regulation of immunological synapse formation
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
negative regulation of extrinsic apoptotic signaling pathway
epithelial cell differentiation
