Invitrogen

Gelsolin Polyclonal Antibody

Gelsolin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Gelsolin Antibody (PA5-27350) in IHC (P)

Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using Gelsolin (Product # PA5-27350) antibody at 1:500 dilution. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.

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产品信息

PA5-27350

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 561 and 782 of Human Gelsolin

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.86 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 20% glycerol

内含物

0.025% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2544826

产品详细信息

Recommended positive controls: H1299, HeLa, human plasma, rat plasma, mouse plasma.

Predicted reactivity: Mouse (94%), Rat (94%), Chicken (81%), Sheep (98%), Bovine (98%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Renal carcinoma/kidney progenitor cell chimera organoid as a novel tumorigenesis gene discovery model.

Disease models & mechanisms

Xu Q,Junttila S,Scherer A,Giri KR,Kivelä O,Skovorodkin I,Röning J,Quaggin SE,Marti HP,Shan J,Samoylenko A,Vainio SJ

PA5-27350 was used in Western Blotting to compare renal ontogenesis control genes to the genes involved in kidney cancer which may provide new growth-associated gene screens in the context of the behavioural roles of cancer cells.