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Ghrelin Antibody (710266) in WB
Western blot analysis of Ghrelin in whole cell extracts from mouse stomach lysate using a Ghrelin Recombinant Rabbit Superclonal™ Antibody (Product # 710266) at a dilution of 2 µg/mL. Samples were detected using chemiluminescence (ECL). Results show a band at ~13kDa.
产品信息
710266
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
克隆号
10HCLC
抗原
Peptide corresponding to amino acids 31-43 of human Ghrelin
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2532654
产品详细信息
This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
靶标信息
GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AMCBX1; Appetite-regulating hormone; FIP-3; FIP3; Fip3p; ghrelin 27; ghrelin 28; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin; ghrelin/obestatin preprohormone; Growth hormone secretagogue; Growth hormone-releasing peptide; IKK-gamma; In2c-preproghrelin; IP; IP1; IP2; IPD2; Motilin-related peptide; NEMO; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin; proghrelin; Protein M46
基因别名: 2210006E23Rik; Ghr; GHRL; m46; MTLRP; MTLRPAP; UNQ524/PRO1066
UniProt ID: (Human) Q9UBU3, (Mouse) Q9EQX0
Entrez Gene ID: (Human) 51738, (Mouse) 58991
activation of MAPK activity
gastric acid secretion
negative regulation of endothelial cell proliferation
glucose metabolic process
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
actin polymerization or depolymerization
adult feeding behavior
response to hormone
hormone-mediated signaling pathway
dendrite development
negative regulation of angiogenesis
growth hormone secretion
positive regulation of insulin secretion
regulation of response to food
positive regulation of appetite
negative regulation of interleukin-1 beta production
negative regulation of locomotion
positive regulation of multicellular organism growth
regulation of cell proliferation
negative regulation of circadian sleep/wake cycle, REM sleep
negative regulation of tumor necrosis factor biosynthetic process
negative regulation of apoptotic process
cortisol secretion
response to estrogen
negative regulation of interleukin-6 biosynthetic process
positive regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of insulin secretion
decidualization
negative regulation of inflammatory response
cartilage development
positive regulation of corticotropin secretion
positive regulation of cortisol secretion
positive regulation of synapse assembly
excitatory postsynaptic potential
positive regulation of growth hormone secretion
positive regulation of growth hormone receptor signaling pathway
positive regulation of protein tyrosine kinase activity
negative regulation of energy homeostasis
positive regulation of energy homeostasis
visual learning
positive regulation of response to food
