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产品信息
PA5-93088
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human GLUD2 (NP_0362162)
偶联物
形式
Liquid
浓度
0.77 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806617
产品详细信息
Immunogen sequence: YLHRFGAKCI AVGESDGSIW NPDGIDPKEL EDFKLQHGSI LGFPKAKPYE GSILEVDCDI LIPAATEKQL TKSNAPRVKA KIIAEGANGP TTPEADKIFL ERNILVIPDL YLNAGGVTVS YFEWLKNLNH VSYGRLTFKY ERDSNYHLLL SVQESLERKF GKHGGTIPIV PTAEFQDSIS GASEKDIVHS ALAYTMERSA RQIMHTAMKY NLGLDLRTAA YVNAIEKVFK VYSEAGVTFT; Positive Samples: A-549, MCF7, THP-1, A-431, Mouse brain, Mouse eye, Rat testis; Cellular Location: Mitochondrion matrix
靶标信息
Glutamate dehydrogenase 2, Glud2, is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. Diseases associated with GLUD2 include Parkinson Disease, Late-Onset and Hyperinsulinemic Hypoglycemia, Familial, 6. Among its related pathways are GABA shunt and Carbon metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GDH 2; GluR delta2; Glutamate dehydrogenase 2, mitochondrial; glutamate dehydrogenase pseudogene 1; testicular secretory protein Li 14
基因别名: GDH2; GLUD2; GLUDP1
UniProt ID: (Human) P49448
Entrez Gene ID: (Human) 2747
