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Glut2 Antibody (600-401-GN3) in IHC (P)
Immunohistochemistry with anti-Glut2 antibody showing Glut2 staining in nucleus and cytoplasm of ductal epithelium and of renal glomeruli in human kidney at 20x and 40x (B & C). Formalin fixed/paraffin embedded sections were subjected to heat induced epitope retrieval (HIER) at pH 6.2 and then incubated with rabbit anti-mouse Glut2 antibody at 4.0 µg/ml for 60 minutes. The reaction was developed using MACH ... View More
产品信息
600-401-GN3
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminal domain of mouse Glut2 protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
内含物
0.01% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This affinity-purified Glut-2 antibody is directed against Glut2 protein. A BLAST analysis was used to suggest cross-reactivity with Glut2 from mouse and rat based on a 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.
靶标信息
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in the gene that encode this protein cause Fanconi-Bickel syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glucose transporter 2; Glucose transporter type 2, liver; GLUT-2; liver-type glucose transporter; solute carrier family 2 (facilitated glucose transporter), member 2; Solute carrier family 2, facilitated glucose transporter member 2
基因别名: AI266973; Glut-2; GLUT2; GTT2; SLC2A2
UniProt ID: (Human) P11168, (Mouse) P14246
Entrez Gene ID: (Human) 6514, (Mouse) 20526, (Rat) 25351
insulin receptor binding
glucose transmembrane transporter activity
hexose transmembrane transporter activity
dehydroascorbic acid transporter activity
D-glucose transmembrane transporter activity
transporter activity
sugar:proton symporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
transport
carbohydrate transport
carbohydrate utilization
glucose transport
proton transport
carbohydrate transmembrane transport
hexose transmembrane transport
glucose import
transmembrane transport
dehydroascorbic acid transport
cation transmembrane transport
carbohydrate metabolic process
hexose transport
response to glucose
fructose transport
response to peptide hormone
regulation of insulin secretion
glucose transmembrane transport
